Etodolac

111

CAS Number41340-25-4
Molecular FormulaC17H21NO3
Molecular Weight287.359
InChI KeyNNYBQONXHNTVIJ-UHFFFAOYSA-N
LogP3.49
Synonyms
  • Etodolac
  • (1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
  • Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-
  • 41340-25-4
  • Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-
  • (.+-.)-Etodolac
  • (RS)-Etodolic acid
  • 1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
  • Acide 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetique
  • Etodine
  • Etodolic acid
  • Etogesic
  • Lodin XL
  • Napilac
  • NSC 282126
  • Ramodar
  • Tedolan
  • Ultradol
  • Zedolac
  • Lodine XL
  • Etodolaco
  • Etodolacum
  • UNII-2M36281008
  • (+-)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
  • 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
  • 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
  • 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid

Applications:

HPLC Method for Analysis of Etodolac

May 10, 2016

14

Etodolac is a pyrenecarboxylic acid and non-steroidal anti-inflammatory drug (NSAID). It reduces pain, swelling, and joint stiffness by blocking the production of certain natural substances that cause inflammation. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Meclizine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

 

Condition

Column Primesep 200, 3.2×100 mm, 5 µm, 100A
Mobile Phase MeCN – 40%
Buffer H3PO4 – 0.1%,
Flow Rate 0.5 ml/min
Detection UV, 270 nm

 

Description

Class of Compounds
Drug,  Acid, Hydrophilic, Ionizable, Supplements
Analyzing Compounds Etodolac

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Etodolac

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.