| CAS Number | 80-43-3 |
|---|---|
| Molecular Formula | C18H22O2 |
| Molecular Weight | 270.373 |
| InChI Key | XMNIXWIUMCBBBL-UHFFFAOYSA-N |
| LogP | 5.50 |
| Synonyms |
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Applications:
HPLC Method for Phenol – Acetone Production and Impurities
December 28, 2018
HPLC method for Phenol – Acetone production and impurities
| Column | Newcrom R1, 4.6×100 mm, 3 µm, 100A |
| Mobile Phase | Gradient MeCN – 10-100%, 20 min |
| Buffer | No |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 207 nm |
| Class of Compounds |
Neutral, Basic, Hydrophobic |
| Analyzing Compounds | Phenol, 2-Phenyl-2-propanol, Acetophenone, Cumene Hydroperoxide, Cumene, Dicumyl Peroxide |
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select optionsCumene
Cumene hydroperoxide
Dicumyl peroxide
Phenol
Separation of Dicumyl peroxide on Newcrom R1 HPLC column
February 16, 2018
Dicumyl peroxide can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select options