Tributylphosphine oxide

Tributylphosphine oxide structural formula

CAS Number814-29-9
Molecular FormulaC12H27OP
Molecular Weight218.321
InChI KeyMNZAKDODWSQONA-UHFFFAOYSA-N
LogP3.61
Synonyms
  • Tributylphosphine oxide
  • Tributyl(oxo)-lambda5-phosphane
  • Phosphorane, tributyl-, oxide
  • 814-29-9
  • BRN 1761977
  • EINECS 212-394-3
  • NSC 41935
  • NSC 65484
  • Tri-n-butylphosphine oxide
  • Trisbutylphosphine oxide
  • Tributylfosfinoxid
  • UNII-W58CDF8S4H

Applications:

Separation of Tributylphosphine oxide on Newcrom R1 HPLC column

February 16, 2018
Separation of Tributylphosphine oxide on Newcrom C18 HPLC column

Tributylphosphine oxide can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Tributylphosphine oxide
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.