Thiamine hydrochloride

Thiamine hydrochloride structural formula

CAS Number67-03-8
Molecular FormulaC12H18Cl2N4OS
Molecular Weight337.261
InChI KeyDPJRMOMPQZCRJU-UHFFFAOYSA-M
LogP-0.161
Synonyms
  • Thiamine hydrochloride
  • 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride--hydrogen chloride (1/1/1)
  • Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, hydrochloride (1:1:1)
  • 67-03-8
  • Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl- chloride, monohydrochloride
  • 3-(4-Amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,?-hydroxyethylthiazolium chloride hydrochloride
  • 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride
  • Aneurine hydrochloride
  • Apate drops
  • Beatine
  • Begiolan
  • Benerva
  • Betabion
  • Betalin S
  • Betaxin
  • Bethiazine
  • Bevitine
  • Biamine
  • Bivatin
  • Clotiamina
  • Eskapen
  • Eskaphen
  • Lixa-Beta
  • Metabolin
  • Slowten
  • Thiadoxine
  • Thiamin chloride
  • Thiamin dichloride
  • Thiamin hydrochloride
  • Thiaminal
  • Thiamine chloride
  • Thiamine chloride hydrochloride
  • Thiamine dichloride
  • Thiamine, chlorhydrate
  • Thiamine, hydrochloride
  • Thiamine, monohydrochloride
  • Thiaminhydrochlorid
  • Thiaminium chloride
  • Thiaminium chloride hydrochloride
  • Thiamol
  • Thiavit
  • Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl- chloride (1:1), hydrochloride (1:1)
  • THIAZOLIUM, 3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-5-(2-HYDROXYETHYL)-4-METHYL CHLORIDE, MO..
  • Tiamidon
  • tiamina, clorhidrato
  • Tiaminal
  • Trophite
  • Vetalin S
  • Vinothiam
  • Vitamin B1 hydrochloride
  • Vitaneuron
  • 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride
  • Betabion hydrochloride
  • Bevitex
  • Bithiamin
  • EINECS 200-641-8
  • FEMA No. 3322
  • NSC 36226
  • Vitamin B hydrochloride
  • Vitamin b(sub 1) hydrochloride
  • Thiamine HCl
  • UNII-M572600E5P
  • Thiaminum hydrochloricum
  • thiamine(2+) dichloride
  • 108631-50-1
  • 63-66-1
  • 70732-86-4

Applications:

Separation of Thiamine hydrochloride on Newcrom R1 HPLC column

February 16, 2018
Separation of Thiamine hydrochloride on Newcrom C18 HPLC column

Thiamine hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Thiamine hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.