Streptozotocin

Streptozotocin structural formula

CAS Number18883-66-4
Molecular FormulaC8H15N3O7
Molecular Weight265.222
InChI KeyZSJLQEPLLKMAKR-GKHCUFPYSA-N
LogP-1.45
Synonyms
  • Streptozotocin
  • 2-Deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranose
  • alpha-D-Glucopyranose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-
  • 18883-66-4
  • Estreptozocin
  • estreptozocina
  • Glucopyranose, 2-deoxy-2-(3-methyl-3-nitrosoureido)
  • Glucopyranose, 2-deoxy-2-(3-methyl-3-nitrosoureido)-, D-
  • NSC 37917
  • NSC 85998
  • streptozocine
  • Streptozoticin
  • Zanosar
  • 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose
  • 2-Deoxy-2-(3-methyl-3-nitrosoureido)-alpha(and beta)-D-glucopyranose
  • EINECS 242-646-8
  • D-Glucose, 2-deoxy-2-(3-methyl-3-nitrosoureido)-
  • N-D-Glucosyl-(2)-N'-nitrosomethylurea
  • NCI-C03167
  • NSC-85998
  • RCRA waste number U206
  • N-D-Glucosyl-(2)-N'-nitrosomethylharnstoff
  • Streptozocinum
  • UNII-5W494URQ81
  • 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
  • N-D-Glucosyl-(2)-N&#39
  • -nitrosomethylharnstoff
  • N-D-Glucosyl-(2)-N'-nitrosomethylurea
  • Streptozocinium
  • streptozocin

Applications:

Separation of Streptozotocin on Newcrom R1 HPLC column

February 16, 2018
Separation of Streptozotocin on Newcrom C18 HPLC column

Streptozotocin can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Streptozotocin
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.