Prednisolone valerate acetate

Prednisolone valerate acetate structural formula

CAS Number72064-79-0
Molecular FormulaC28H38O7
Molecular Weight486.606
InChI KeyDGYSDXLCLKPUBR-SLPNHVECSA-N
LogP3.98
Synonyms
  • Prednisolone valerate acetate
  • (11beta)-21-(Acetyloxy)-11-hydroxy-3,20-dioxopregna-1,4-dien-17-yl pentanoate
  • Pentanoic acid, (11beta)-21-(acetyloxy)-11-hydroxy-3,20-dioxopregna-1,4-dien-17-yl ester
  • 72064-79-0
  • 21-(Acetyloxy)-11-beta-hydroxy-17-((1-oxopentyl)oxy)pregna-1,4-diene-3,20-dione
  • BRN 2713941
  • EINECS 276-312-8
  • Lidomex
  • Prednisolone 17-valerate 21-acetate
  • Prednisolone-17-valerate-21-acetate
  • 11-beta,17-alpha,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-acetate 17-valerate
  • UNII-2JB27QJW3D

Applications:

Separation of Prednisolone valerate acetate on Newcrom R1 HPLC column

February 16, 2018
Separation of Prednisolone valerate acetate on Newcrom C18 HPLC column

Prednisolone valerate acetate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Prednisolone valerate acetate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.