Phenobarbital sodium

Phenobarbital sodium structural formula

CAS Number57-30-7
Molecular FormulaC12H11N2NaO3
Molecular Weight254.221
InChI KeyWRLGYAWRGXKSKG-UHFFFAOYSA-M
LogP0.337
Synonyms
  • Phenobarbital sodium
  • Sodium 5-ethyl-4,6-dioxo-5-phenyl-1,4,5,6-tetrahydropyrimidin-2-olate
  • 4,6(1H,5H)-Pyrimidinedione, 5-ethyl-2-hydroxy-5-phenyl-, sodium salt (1:1)
  • 57-30-7
  • Phenobarbital, sodium
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-, monosodium salt
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-, sodium salt (1:1)
  • 5-Ethyl-5-phenylbarbituric acid sodium
  • Barbituric acid, 5-ethyl-5-phenyl-, sodium salt
  • fenobarbital sodico
  • Gardenal sodium
  • Linasen
  • Luminal sodium
  • Phenemalum
  • Phenobal
  • Phenobal sodium
  • phenobarbital sodique
  • Phenobarbitalnatrium
  • Phenobarbitone sodium
  • Sodium 5-ethyl-5-phenylbarbiturate
  • Sodium ethylphenylbarbiturate
  • Sodium luminal
  • Sodium phenobarbital
  • Sodium phenobarbitone
  • Sodium phenylethylbarbiturate
  • Sodium phenylethylmalonylurea
  • Sol phenobarbital
  • Sol phenobarbitone
  • Soluble phenobarbital
  • Soluble phenobarbitone
  • EINECS 200-322-3
  • 5-Ethyl-5-phenylbarbituric acid sodium salt
  • 5-Ethyl-5-phenyl-2,4,6-(1H,3H,5H)pyrimidinetrione monosodium salt
  • Phenemalnatrium
  • Phenobarbital elixir
  • Phenobarbital Na
  • Phenobarbitone sodium salt
  • Phenobarbiton-natrium
  • Phenylethylbarbituric acid, sodium salt
  • Fenobarbital natrium
  • Phenobarbitalum natricum
  • UNII-SW9M9BB5K3
  • Phenobarbital sodium salt
  • Phenyl-aethyl-barbitursaeure natrium
  • Sodium phenobarbitone
  • Sodium phenobarbiturate

Applications:

Separation of Phenobarbital sodium on Newcrom R1 HPLC column

February 16, 2018
Separation of Phenobarbital sodium on Newcrom C18 HPLC column

Phenobarbital sodium can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Phenobarbital sodium
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.