Ondansetron

Ondansetron structural formula

CAS Number99614-02-5
Molecular FormulaC18H19N3O
Molecular Weight293.370
InChI KeyFELGMEQIXOGIFQ-UHFFFAOYSA-N
LogP2.53
Synonyms
  • Ondansetron
  • 9-Methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
  • 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-
  • 99614-02-5
  • 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-
  • BRN 3622981
  • 1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one
  • UNII-4AF302ESOS
  • Zuplenz
  • Ondansetron Injection
  • 108303-49-7
  • 116002-70-1
  • 808754-64-5

Applications:

HPLC Method for Analysis of Ondansetron

May 6, 2016

Chr_1070




Ondansetron is a competitive serotonin type 3 receptor antagonist. It is used to prevent nausea and vomiting caused by chemotherapy by reducing the activity of the vagus nerve and blocking of serotonin receptors. Some of the drug’s most common side effects are headaches, constipation, and dizziness. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Ondansetron. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Ondansetron
Ondansetron hydrochloride dihydrate
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.