OligoMg is a cutting-edge oligonucleotide-specific column that employs the innovative Bridge Ion Separation Technique (BIST). This advanced technology excels in the efficient separation of multi-charged compounds, such as negatively charged oligonucleotides.
Features:
- Silica-Based Cation-Exchange Column: Features a negatively charged surface Dynamic Loading with Mg²⁺: The column is dynamically loaded with a doubly charged positive ion (Mg²⁺), which, in the presence of an organic modifier in the mobile phase, creates a bridge between the negatively charged stationary phase and the negatively charged oligonucleotides.
- Mobile Phase: Operates effectively with only H₂O/MeCN in the mobile phase.
Benefits:
- Efficient Separation: Superior separation of multi-charged oligonucleotides.
- Innovative Technology: Utilizes the cutting-edge BIST for enhanced performance.
- Simplified Mobile Phase: Eliminates the need for an ionic modifier in the mobile phase.
- Different selectivity: Different mechanism of interaction provides different selectivity toward type and number nucleobases
- Specificity: Retains only oligonucleotides, any hydrophobic molecules will not be retained.
Experience the unparalleled performance of OligoMg for your oligonucleotide separation needs.
