Moexipril hydrochloride

Moexipril hydrochloride structural formula

CAS Number82586-52-5
Molecular FormulaC27H35ClN2O7
Molecular Weight535.031
InChI KeyJXRAXHBVZQZSIC-JKVLGAQCSA-N
LogP3.03
Synonyms
  • Moexipril hydrochloride
  • (3S)-2-{N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid--hydrogen chloride (1/1)
  • 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, (3S)-, hydrochloride (1:1)
  • 82586-52-5
  • RS 10085-197
  • Univasc
  • Moexipril HCl
  • UNII-Q1UMG3UH45

Applications:

Separation of Moexipril hydrochloride on Newcrom R1 HPLC column

May 16, 2018
Separation of Moexipril hydrochloride on Newcrom R1 HPLC column

Moexipril hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Moexipril hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.