Isosorbide 5-mononitrate

Isosorbide 5-mononitrate structural formula

CAS Number16051-77-7
Molecular FormulaC6H9NO6
Molecular Weight191.139
InChI KeyYWXYYJSYQOXTPL-SLPGGIOYSA-N
LogP-0.150
Synonyms
  • Isosorbide 5-mononitrate
  • 1,4:3,6-Dianhydro-5-O-nitro-D-glucitol
  • D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate
  • 16051-77-7
  • 1,4:3,6-Dianhydro-5-O-nitro-D-glucitol
  • D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate
  • 1,4:3,6-Dianhydro-D-glucitol 5-nitrate
  • Conpin Retardkaps
  • Corangin
  • Corangin SR
  • Dilavenil
  • Elantan
  • Elantan Long
  • Elantan Retard
  • Geomatrix
  • Glucitol, 1,4:3,6-dianhydro-, 5-nitrate, D-
  • Imdur Durules
  • Imtrate
  • Ismexin
  • Isomonat
  • Isomonit
  • Isosorbide mononitrate
  • Isosorbide 5-nitrate
  • Isosorbidmononitrat
  • Medocor
  • Momo Mack
  • Monicor
  • Monizid
  • Mono Corax
  • Mono Corax Retard
  • Mono-Cedocard
  • Monoclair
  • Monocord 20
  • Monocord 40
  • Monocord 50SR
  • Monodur Durules
  • Monoket
  • Monoket OD
  • Monoket Retard
  • Monolong
  • Monolong 40
  • Monolong 60
  • Mono-Mack
  • Mononit
  • Mononit Retard 50
  • mononitrate d'isosorbide
  • mononitrato de isosorbida
  • Monopront
  • Mono-Sanorania
  • Monosorb
  • Monosorbitrate
  • Monosordil
  • Monotrate
  • Monovas
  • Multitab
  • Nitramin
  • Olicard
  • Pentacard
  • Pentacard 20
  • BRN 5851319
  • EINECS 240-197-2
  • Edistol
  • Epicordin
  • Etimonis
  • Fem-Mono
  • ISMN AbZ
  • ISMN AL
  • ISMN Apogepha
  • ISMN Atid
  • ISMN Basics
  • ISMN Heumann
  • ISMN Hexal
  • ISMN Lannacher
  • ISMN Stada
  • Mono Mack
  • Monocord 50 SR
  • MonoSigma
  • Olicardin
  • Orasorbil
  • Percorina
  • Promocard
  • Sigacora
  • Sorbimon
  • Titarane
  • Turimonit
  • Vasdilat
  • vasotrate
  • Isosorbidi mononitras
  • UNII-LX1OH63030

Applications:

Separation of Isosorbide 5-mononitrate on Newcrom R1 HPLC column

May 16, 2018
Separation of Isosorbide 5-mononitrate on Newcrom R1 HPLC column

Isosorbide 5-mononitrate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Isosorbide 5-mononitrate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.