Homatropine hydrobromide

Homatropine hydrobromide structural formula

CAS Number51-56-9
Molecular FormulaC16H22BrNO3
Molecular Weight356.261
InChI KeyDWSGTFTVBLXELC-RDYJJYPNSA-N
LogP1.56
Synonyms
  • Homatropine hydrobromide
  • (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl hydroxy(phenyl)acetate--hydrogen bromide (1/1)
  • Benzeneacetic acid, alpha-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1)
  • 51-56-9
  • Benzeneacetic acid, alpha-hydroxy-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1)
  • (+/-)-Homatropine bromide
  • Mandelic acid tropine ester hydrobromide
  • 1alphaH,5alphaH-Tropan-3alpha-ol, mandelate (ester), hydrobromide
  • Benzeneacetic acid, alpha-hydroxy-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, HBr, endo-(+-)
  • EINECS 200-105-3
  • Homatropine (bromhydrate d')
  • (+-)-Homatropine bromide
  • Homatropini bromidum
  • Homatropini hydrobromidum
  • Homatropinum hydrobromicum
  • Homatropine dl- hydrobromide
  • UNII-BEW7469QZ0

Applications:

Separation of Homatropine hydrobromide on Newcrom R1 HPLC column

February 16, 2018
Separation of Homatropine hydrobromide on Newcrom C18 HPLC column

Homatropine hydrobromide can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Homatropine hydrobromide
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.