Clindamycin phosphate

Clindamycin phosphate structural formula

CAS Number24729-96-2
Molecular FormulaC18H34ClN2O8PS
Molecular Weight504.960
InChI KeyUFUVLHLTWXBHGZ-MGZQPHGTSA-N
LogP0.541
Synonyms
  • Clindamycin phosphate
  • Methyl 7-chloro-6,7,8-trideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-2-O-phosphono-1-thio-L-threo-alpha-D-galacto-octopyranoside
  • L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-(dihydrogen phosphate)
  • 24729-96-2
  • CLINDAMYCIN PO4
  • 7(S)-Chloro-7-deoxylincomycin 2-phosphate
  • Cleocin T
  • Cleocin phosphate
  • Clindamycin 2-phosphate
  • Dalacin P
  • EINECS 246-433-0
  • Evoclin
  • Clindamycin dihydrogenphosphat
  • Clindamycin-2-dihydrogenphosphat
  • Cleocin phosphate in dextrose 5% in plastic container
  • Clinda-Derm
  • Clindagel
  • Clindamycin phosphate in dextrose 5%
  • Clindamycin phosphate in dextrose 5% in plastic container
  • Clindesse
  • Clindets
  • Clindamax
  • Clindamycin injection
  • UNII-EH6D7113I8

Applications:

Separation of Clindamycin phosphate on Newcrom R1 HPLC column

February 16, 2018
Separation of Clindamycin phosphate on Newcrom C18 HPLC column

Clindamycin phosphate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Clindamycin phosphate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.