Chlormadinone acetate

Chlormadinone acetate structural formula

CAS Number302-22-7
Molecular FormulaC23H29ClO4
Molecular Weight404.930
InChI KeyQMBJSIBWORFWQT-DFXBJWIESA-N
LogP3.66
Synonyms
  • Chlormadinone acetate
  • 6-Chloro-3,20-dioxopregna-4,6-dien-17-yl acetate
  • Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-chloro-
  • 302-22-7
  • Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-chloro-
  • 17-Acetoxy-6-chloro-6-dehydroprogesterone
  • 17-Acetoxy-6-chloropregna-4,6-diene-3,20-dione
  • 17?-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione
  • 17?-Acetoxy-6-chloro-6,7-dehydroprogesterone
  • 6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione
  • 6-Chloro-17-hydroxypregna-4,6-diene-3,20-dione acetate
  • 6-Chloro-17?-acetoxy-4,6-pregnadiene-3,20-dione
  • 6-Chloro-17?-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate
  • 6-Chloro-17?-hydroxypregna-4,6-diene-3,20-dione acetate
  • 6-Chloro-17?-hydroxy-?6-progesterone acetate
  • 6-Chloro-6,7-dehydro-17-acetoxyprogesterone
  • 6-Chloro-6-dehydro-17-acetoxyprogesterone
  • 6-Chloro-6-dehydro-17?-acetoxyprogesterone
  • 6-Chloro-pregna-4,6-dien-17?-ol-3,20-dione acetate
  • 6-Chloro-?4,6-pregnadien-17?-ol-3,20-dione 17-acetate
  • 6-Chloro-?6-[17?]acetoxyprogesterone
  • 6-Chloro-?6-17-acetoxyprogesterone
  • 6-Chloro-?6-dehydro-17-acetoxyprogesterone
  • 6-Dehydro-6-chloro-17?-acetoxyprogesterone
  • acetate de chlormadinone
  • acetato de clormadinona
  • Bovisynchron
  • Chloramdinone acetate
  • Chlormadinon acetate
  • Chlormadinonacetat
  • Chloromadinone acetate
  • Chronosyn
  • Clordion
  • Cyclonorm
  • Fertiletten
  • Gestafortin
  • Luteran
  • Lutinyl
  • Menstridyl
  • Normenon
  • NSC 92338
  • Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-, acetate
  • Prostal
  • Skedule TM
  • Synchrosyn
  • Synchrosyn P
  • Traslan
  • 17alpha-Acetoxy-6-chloro-6-dehydroprogesterone
  • 17-alpha-Acetoxy-6-chloro-6-dehydroprogesterone
  • 17-alpha-Acetoxy-6-chloro-6,7-dehydroprogesterone
  • 17-alpha-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione
  • 17-(Acetyloxy)-6-chloropregna-4,6-diene-3,20-dione
  • Chlordion
  • 6-Chloro-17-alpha-acetoxy-4,6-pregnadiene-3,20-dione
  • 6-Chloro-delta6-17-acetoxyprogesterone
  • 6-Chloro-delta6-(17alpha)acetoxyprogesterone
  • 6-Chloro-6-dehydro-17-alpha-acetoxyprogesterone
  • 6-Chloro-6-dehydro-17alpha-acetoxyprogesterone
  • 6-Chloro-6-dehydro-17-alpha-hydroxyprogesterone acetate
  • 6-Chloro-6-dehydro-17alpha-hydroxyprogesterone acetate
  • 6-Chloro-17alpha-hydroxypregna-4,6-diene-3,20-dione acetate
  • 6-Chloro-delta-6-17alpha-hydroxyprogesterone acetate
  • 6-Chloro-17-alpha-hydroxy-delta(sup 6)-progesterone acetate
  • 6-Chloro-pregna-4,6-dien-17alpha-ol-3,20-dione acetate
  • 6-Chloro-pregna-4,6-dien-17-alpha-ol-3,20-dione acetate
  • 6-Chloro-delta(sup 6)-17-acetoxyprogesterone
  • 6-Chloro-delta(sup 6)-dehydro-17-acetoxyprogesterone
  • 6-Chloro-delta(sup 4,6)-pregnadiene-17-alpha-ol-3,20-dione 17-acetate
  • 6-Dehydro-6-chloro-17-alpha-acetoxyprogesterone
  • EINECS 206-118-0
  • Minipill
  • NSC-92338
  • Pregna-4,6-diene-3,20-dione, 17-(acetoxy)-6-chloro-
  • Progesterone, 6-chloro-6-dehydro-17-hydroxy-, acetate
  • Skedule
  • delta(sup 6)-6-Chloro-17-alpha-acetoxyprogesterone
  • delta(sup 6)-6-Chloro-17alpha-acetoxyprogesterone
  • Chlormadinonu
  • UNII-0SY050L61N

Applications:

Separation of Chlormadinone acetate on Newcrom R1 HPLC column

February 16, 2018
Separation of Chlormadinone acetate on Newcrom C18 HPLC column

Chlormadinone acetate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Chlormadinone acetate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.