Cephaloglycin

Cephaloglycin structural formula

CAS Number3577-01-3
Molecular FormulaC18H19N3O6S
Molecular Weight405.430
InChI KeyFUBBGQLTSCSAON-PBFPGSCMSA-N
LogP0.0559
Synonyms
  • Cephaloglycin
  • (6R,7R)-3-[(Acetyloxy)methyl]-7-{[(2R)-2-amino-2-phenylacetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2R)-2-amino-2-phenylacetyl]amino]-8-oxo-, (6R,7R)-
  • 3577-01-3
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2R)-aminophenylacetyl]amino]-8-oxo-, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[(aminophenylacetyl)amino]-8-oxo-, [6R-[6?,7?(R*)]]-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2R)-2-amino-2-phenylacetyl]amino]-8-oxo-, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-(2-amino-2-phenylacetamido)-3-(hydroxymethyl)-8-oxo-, acetate (ester), D-
  • 7-(2-D-?-Aminophenylacetamido)cephalosporanic acid
  • 7-(D-?-Aminophenylacetoamido)-cephalosporanic acid
  • cefaloglicina
  • cefaloglycin
  • cefaloglycine
  • Cephaloglycine
  • D-(-)-Cephaloglycin
  • D-Cephaloglycine
  • Kafocin
  • Kefglycin
  • Lilly 39435
  • 3-((Acetyloxy)methyl)-7-((aminophenylacetyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
  • 7-(D-2-Amino-2-phenylacetamido)-3-acetoxymethyl-delta(sup 3)-cephem-4-carboxylic acid
  • 7-(2-D-alpha-Aminophenylacetamido)cephalosporanic acid
  • 7-(2-Amino-2-phenylacetamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)octane-2-carboxylic acid, acetate inner salt
  • EINECS 222-696-7
  • Cefaloglycinum
  • UNII-HD2D469W6U
  • 7-(D-2-Amino-2-phenylacetamido)-3-acetoxymethyl-delta(sup3)-cephem-4-carboxylic acid
  • 7-(D-alpha-Aminophenyl-acetamido)cephalosporanic acid
  • CEG
  • Cephaloglycin anhydrous
  • Cephaoglycin acid

Applications:

Separation of Cephaloglycin on Newcrom R1 HPLC column

February 16, 2018
Separation of Cephaloglycin on Newcrom C18 HPLC column

Cephaloglycin can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Cephaloglycin
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.