Selectivity

Separation of Insulin Analogs:
Closely related peptides can be difficult to separate by reverse phase.
By combining ionic and hydrophobic interactions, Promix MP is able to separate these analogs, differing in sequence by a single amino acid pair, using the slight differences in pI as illustrated below.
 

Normal human insulin

 

 

 

 

Synthetic insulin Humalog

 

 

 

 

Sythetic insulin Lantus