1,3-Bis(2-methylphenyl)guanidine

1,3-Bis(2-methylphenyl)guanidine structural formula

CAS Number97-39-2
Molecular FormulaC15H17N3
Molecular Weight239.323
InChI KeyOPNUROKCUBTKLF-UHFFFAOYSA-N
LogP3.17
Synonyms
  • 1,3-Bis(2-methylphenyl)guanidine
  • N,N'-Bis(2-methylphenyl)guanidine
  • Guanidine, N,N'-bis(2-methylphenyl)-
  • 97-39-2
  • 1,3-Bis(o-tolyl)guanidine
  • BRN 2653884
  • Diorthotolylguanidine
  • 1,3-Di-o-tolyguanidine
  • Di-o-tolylguanidine
  • N,N'-Di-o-tolylguanidine
  • DOTG accelerator
  • EINECS 202-577-6
  • Eveite DOTG
  • Guanidine, 1,3-di(2-tolyl)-
  • NSC 132023
  • USAF A-6598
  • Vulkacit DOTG
  • Vulkacit dotg/C
  • Vulkacite DOTG
  • Akrochem DOTG
  • N,N'-Di-o-tolueylguanidine
  • Nocceler DT
  • Sanceler DT
  • Soxinol DT
  • Vulcafor DOTG
  • NSC 473
  • UNII-LL2P01I17O
  • 132116-33-7
  • 46913-50-2
  • 60297-72-5

Applications:

Separation of 1,3-Bis(2-methylphenyl)guanidine on Newcrom R1 HPLC column

February 16, 2018
Separation of 1,3-Bis(2-methylphenyl)guanidine on Newcrom C18 HPLC column

1,3-Bis(2-methylphenyl)guanidine can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
1,3-Bis(2-methylphenyl)guanidine
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.