Pioglitazone

Pioglitazone structural formula

CAS Number111025-46-8
Molecular FormulaC19H20N2O3S
Molecular Weight356.441
InChI KeyHYAFETHFCAUJAY-UHFFFAOYSA-N
LogP2.91
Synonyms
  • Pioglitazone
  • 5-({4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione
  • 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-
  • 111025-46-8
  • 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-
  • Pioglitazona
  • Pioglitazonum
  • UNII-X4OV71U42S
  • Piozone
  • (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione

Applications:

HPLC Method for Analysis of Pioglitazone

May 3, 2016

Chr_1062




Pioglitazone is thiazolidinedione with antidiabetic properties, meaning it is a diabetes drug. It activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), and works correctly only if used along a proper diet and exercise to control high blood sugar in patients with type 2 diabetes.Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Pioglitazone. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Pioglitazone
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.