Fluticasone propionate

Fluticasone propionate structural formula

CAS Number80474-14-2
Molecular FormulaC25H31F3O5S
Molecular Weight500.571
InChI KeyWMWTYOKRWGGJOA-ZHLGSTKJSA-N
LogP3.47
Synonyms
  • Fluticasone propionate
  • (6alpha,8xi,11beta,16alpha,17alpha)-6,9-Difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propanoate
  • Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, S-(fluoromethyl) ester, (6alpha,8xi,11beta,16alpha,17alpha)-
  • 80474-14-2
  • Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, S-(fluoromethyl) ester, (6?,11?,16?,17?)-
  • Atemur Mite
  • Cutivate
  • Cutivate cream
  • Cyclesonide
  • Flixonase
  • Flixonase Nasal Spray
  • Flixotide
  • Flixotide Disk
  • Flixotide Disks
  • Flixotide Inhaler
  • Flonase
  • Flonase Aq
  • Flovent
  • Flovent Diskus
  • Flunase
  • Fluticasone 17-propionate
  • Flutide
  • Flutide N
  • Flutivate
  • Asmatil
  • Axotide
  • Brethal
  • Fluinol
  • Flusonal
  • Fluspiral
  • Fluticasonpropionat Allen
  • Inalacor
  • Rinosone
  • Trialona
  • Flovent HFA
  • Flovent Diskus 100
  • Flovent Diskus 250
  • Flovent Diskus 50
  • UNII-O2GMZ0LF5W
  • Flovent-hfa
  • Cultivate

Applications:

HPLC Method for Analysis of Fluticasone Propionate in Nasal Spray on Newcrom R1 Column

June 11, 2018

 

Condition
Column Newcrom R1 3.2×100 mm, 3 µm, 100A
Mobile Phase MeCN/H2O – 70/30%
Buffer H3PO4 – 0.1 %
Flow Rate 0.5 ml/min
Detection UV, 238 nm

 

Description
Class of Compounds
 Drug,  Hydrophobic, Neutral
Analyzing Compounds Fluticasone Propionate

 

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Fluticasone propionate
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.