Dehydrocholic acid

Dehydrocholic acid structural formula

CAS Number81-23-2
Molecular FormulaC24H34O5
Molecular Weight402.532
InChI KeyOHXPGWPVLFPUSM-KLRNGDHRSA-N
LogP2.61
Synonyms
  • Dehydrocholic acid
  • (5beta)-3,7,12-Trioxocholan-24-oic acid
  • Cholan-24-oic acid, 3,7,12-trioxo-, (5beta)-
  • 81-23-2
  • 4-10-00-03478
  • Bilidren
  • Bilostat
  • Biochol
  • BRN 3226734
  • Cholagon
  • Cholan DH
  • 5beta-Cholanic acid, 3,7,12-trioxo-
  • Cholan-24-oic acid, 3,7,12-trioxo-, (5-beta)-
  • Cholic acid, dehydro-
  • Cholimed
  • Chologon
  • Dehychol
  • Dehycol
  • Dehycon
  • Dehystolin
  • Deidrocolico Vita
  • Didocol
  • Didrocolo
  • Dilabil
  • Doxycholpotassium
  • Drenobyl
  • EINECS 201-335-7
  • Erebile
  • Felacrinos
  • Hykolex
  • Ketochol
  • Ketocholanic acid
  • Khologon
  • Novocolin
  • NSC 8796
  • Oxycholin
  • Procholon
  • Sanocholen
  • Triketocholanic acid
  • 3,7,12-Triketo-5beta-cholanoic acid
  • 3,7,12-Trioxo-5-beta-cholan-24-oic acid
  • Acide dehydrocholique
  • Acido dehidrocolico
  • Acido deidrocolico
  • Acidum dehydrocholicum
  • Dehydrocholsaeure
  • UNII-NH5000009I
  • 3,7,12-triketocholanic acid
  • 3,7,12-trioxo-5beta-cholanic acid
  • 3,7,12-trioxocholanic acid
  • Decholin

Applications:

Separation of Dehydrocholic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of Dehydrocholic acid on Newcrom C18 HPLC column

Dehydrocholic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Dehydrocholic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.