Amphetamine

Amphetamine structural formula

CAS Number300-62-9
Molecular FormulaC9H13N
Molecular Weight135.211
InChI KeyKWTSXDURSIMDCE-UHFFFAOYSA-N
LogP1.76
Synonyms
  • Amphetamine
  • 1-Phenylpropan-2-amine
  • Benzeneethanamine, alpha-methyl-
  • 300-62-9
  • Benzeneethanamine, α-methyl-
  • (.+-.)-1-Phenyl-2-aminopropane
  • (.+-.)-Desoxynorephedrine
  • (.+-.)-Phenylisopropylamine
  • (.+-.)-α-Methylphenethylamine
  • (.+-.)-α-Methylphenylethylamine
  • (.+-.)-β-Phenylisopropylamine
  • 1-Benzylethylamine
  • 1-Methyl-2-phenylethylamine
  • 1-Phenyl-2-aminopropane
  • 1-Phenyl-2-propanamine
  • 1-Phenyl-2-propylamine
  • 2-Amino-1-phenylpropane
  • 3-Phenyl-2-propylamine
  • Actedron
  • Adderall
  • Adderall XR
  • Allodene
  • amfetamina
  • Amfetamine
  • Amphetamin
  • Anorexine
  • Benzebar
  • Benzedrine
  • Benzeneethanamine, α-methyl-, (.+-.)-
  • Benzolone
  • Desoxynorephedrine
  • dl-α-Methylphenethylamine
  • Elastonon
  • Fenopromin
  • Isoamyne
  • Mecodrin
  • Norephedrane
  • Novydrine
  • NSC 27159
  • Oktedrin
  • Ortedrine
  • Percomon
  • Phenamine
  • Phenedrine
  • Phenethylamine, α-methyl-, (.+-.)-
  • Profamina
  • Propisamine
  • Racemic Amphetamine
  • Raphetamine
  • Rhinalator
  • Simpatedrin
  • Simpatina
  • Sympamine
  • Sympatedrine
  • Weckamine
  • α-Methylbenzeneethanamine
  • α-Methylphenethylamine
  • α-Methylphenylethylamine
  • α-Methyl-β-phenylethylamine
  • β-Aminopropylbenzene
  • β-Phenylisopropylamine
  • beta-Aminopropylbenzene
  • Anorexide
  • (+-)-Benzedrine
  • EINECS 200-458-3
  • EINECS 206-096-2
  • (+-)-alpha-Methylbenzeneethanamine
  • alpha-Methylbenzeneethaneamine
  • (+-)-alpha-Methylphenylethylamine
  • Mydrial
  • Phenethylamine, alpha-methyl-, (+-)-
  • (Phenylisopropyl)amine
  • Protioamphetamine
  • racemic-Desoxynor-ephedrine
  • (+-)-alpha-Methylphenethylamine
  • dl-alpha-Methylphenethylamine
  • 1-Phenyl-2-amino-propan
  • Amfetaminum
  • Anfetamina
  • beta-Phenylisopropylamin
  • Fenylo-izopropylaminyl
  • UNII-CK833KGX7E
  • 3-Amino-1-propylbenzene
  • Amphetamine mixture with Dextroamphetamine
  • Delcobese
  • Dextroamp saccharate, amp aspartate, dextroamp sulfate and amp sulfate
  • Amphetamine salts
  • 17108-96-2
  • 60-15-1
  • 96332-84-2

Applications:

HPLC Method for Analysis of Amphetamine

May 10, 2016

88

Amphetamine is a drug that stimulates the central nervous system. It is used to treat ADD, narcolepsy, and obesity. Amphetamine can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particle columns are available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation of impurities in preparative separation. It also suitable for pharmacokinetics.

 

Condition
Column Primesep 200, 3.2×100 mm, 5 µm, 100A
Mobile Phase MeCN – 40%
Buffer H3PO4 – 0.1%,
Flow Rate 0.5 ml/min
Detection UV, 270 nm

 

Description
Class of Compounds
 Drug,  Acid, Hydrophilic, Ionizable, Supplements
Analyzing Compounds Amphetamine

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Amphetamine
Amphetamine sulfate
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.