Puromycin aminonucleoside

Puromycin aminonucleoside structural formula

CAS Number58-60-6
Molecular FormulaC12H18N6O3
Molecular Weight294.316
InChI KeyRYSMHWILUNYBFW-GRIPGOBMSA-N
LogP-0.619
Synonyms
  • Puromycin aminonucleoside
  • 3'-Amino-3'-deoxy-N,N-dimethyladenosine
  • Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl-
  • 58-60-6
  • 4-26-00-03697
  • Aminonucleoside
  • Aminonucleoside puromycin
  • BRN 0093902
  • 6-Dimethylamino-9-(3'-ribosylamine)purine
  • EINECS 200-388-3
  • NSC 3056
  • UNII-0Q580U88V8
  • (2R,3R,4S,5S)-4-amino-2-[6-(dimethylamino)-9H-purin-9-yl]-5-(hydroxymethyl)tetrahydro-3-furanol
  • 3'-Amino-3'-deoxy-N6,N6-dimethyladenosine
  • 3'-amino-3'-deoxy-N,N-dimethyladenosine
  • 6-Dimethylamino-9-(3'-ribosylamine)purine
  • Stylomycin aminonucleoside
  • 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
  • 136680-68-7
  • 28315-29-9
  • 54833-68-0

Applications:

Separation of Puromycin aminonucleoside on Newcrom R1 HPLC column

February 19, 2018


Puromycin aminonucleoside can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.


Separation of Puromycin aminonucleoside on Newcrom C18 HPLC column

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Puromycin aminonucleoside
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.