Pidolic acid

Pidolic acid structural formula

CAS Number98-79-3
Molecular FormulaC5H7NO3
Molecular Weight129.116
InChI KeyODHCTXKNWHHXJC-VKHMYHEASA-N
LogP-1.74
Synonyms
  • Pidolic acid
  • 5-Oxo-L-proline
  • L-Proline, 5-oxo-
  • 98-79-3
  • L-Proline, 5-oxo-
  • (-)-2-Pyrrolidone-5-carboxylic acid
  • (-)-Pyroglutamic acid
  • (2S)-5-Oxopyrrolidine-2-carboxylic acid
  • (5S)-2-Oxopyrrolidine-5-carboxylic acid
  • (S)-(-)-2-PYRROLIDINONE-5-CARBOXYLIC ACID
  • (S)-(-)-2-Pyrrolidone-5-carboxylic acid
  • (S)-(-)-?-Butyrolactam-?-carboxylic acid
  • (S)-2-Pyrrolidone-5-carboxylic acid
  • (S)-5-Oxo-2-pyrrolidinecarboxylic acid
  • (S)-Pyroglutamic acid
  • 2-L-Pyrrolidone-5-carboxylic acid
  • 2-Oxopyrrolidine-5(S)-carboxylic acid
  • 2-Pyrrolidinone-5-carboxylic acid
  • 2-Pyrrolidon-5-carboxylic acid
  • 2-PYRROLIDONE CARBOXYLIC ACID
  • 5-Carboxy-2-pyrrolidinone
  • 5-Oxo-L-proline
  • 5-Oxoproline
  • 5-Pyrrolidinone-2-carboxylic acid
  • Acide pidolique
  • acido pidolico
  • Ajidew A 100
  • Glutimic acid
  • Glutiminic acid
  • L-2-Pyrrolidone-5-carboxylic acid
  • L-5-Carboxy-2-pyrrolidinone
  • L-5-Oxo-2-pyrrolidinecarboxylic acid
  • L-5-Oxoproline
  • L-Glutamic acid, ?-lactam
  • L-Glutimic acid
  • L-Glutiminic acid
  • L-Pyroglutamic acid
  • L-Pyrrolidinonecarboxylic acid
  • L-Pyrrolidonecarboxylic acid
  • NSC 143034
  • Oxoproline
  • Oxopyrrolidinecarboxylic acid
  • Pidolidone
  • Pidolinsaure
  • Proline, 5-oxo-, L-
  • Pyroglutamic acid
  • PYRROLID-2-ONE-5-CARBOXYLIC ACID
  • Pyrrolidinonecarboxylic acid
  • Pyrrolidone-5-carboxylic acid
  • Pyrrolidonecarboxylic acid
  • AJIDEW A-100
  • 2-Benzothiazolesulfenic acid morpholide
  • EINECS 202-700-3
  • L-Glutamic acid gamma-lactam
  • 2-Oxopyrrolidine-5-carboxylic acid
  • Proline, 5-oxo-
  • 2-Pyrrolidone-5-carboxylate
  • NSC 9966
  • Acidum pidolicum
  • UNII-SZB83O1W42
  • 5-L-Oxoproline
  • Pidolate
  • 5-Pyrrolidone-2-carboxylic acid
  • Pyroglutamate
  • Pyroglutamic acid
  • 16891-48-8
  • 29222-42-2
  • 312618-42-1
  • 498-91-9
  • 6886-28-8
  • 87430-62-4
  • 95650-42-3

Applications:

Separation of Pidolic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of Pidolic acid on Newcrom C18 HPLC column

Pidolic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Pidolic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.