Etidronate disodium

Etidronate disodium structural formula

CAS Number7414-83-7
Molecular FormulaC2H6Na2O7P2
Molecular Weight249.991
InChI KeyGWBBVOVXJZATQQ-UHFFFAOYSA-L
LogP-2.36
Synonyms
  • Etidronate disodium
  • Disodium (1-hydroxyethane-1,1-diyl)bis[hydrogen (phosphonate)]
  • Phosphonic acid, (1-hydroxyethylidene)bis-, sodium salt (1:2)
  • 7414-83-7
  • Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt
  • Diphos
  • Didronel
  • Disodium dihydrogen (1-hydroxyethylidene)bisphosphonate
  • Disodium ethane-1-hydroxy-1,1-diphosphonate
  • (1-Hydroxyethylidene)bisphosphonic acid disodium salt
  • 1-Hydroxyethane-1,1-diphosphonic acid disodium salt
  • 1-HYDROXYETHYLIDENE-BIS-PHOSPHONIC ACID, DISODIUM SALT
  • BIS(1-HYDROXYETHYLIDENE)PHOSPHONATE, DISODIUM
  • Calcimux
  • Chelest PH 212
  • Didronel R
  • dihidrogeno(1-hidroxietiliden)bisfosfonato de disodio
  • dihydrogeno(1-hydroxyethylidene)bisphosphonate de disodium
  • Dihydrogeno(1-hydroxyethylidene)diphosphonate de disodium
  • Dinatriumdihydrogen(1-hydroxyethyliden)bisphosphonat
  • Disodium (1-hydroxyethylidene)-1,1-bisphosphonate
  • Disodium (1-hydroxyethylidene)-1,1-diphosphonate
  • DISODIUM (1-OH-ETHYLIDENE)BISPHOSPHONATE
  • Disodium 1-hydroxy-1,1-ethanediphosphonate
  • Disodium 1-hydroxyethane-1-diphosphonate
  • Disodium 1-hydroxyethanediphosphonate
  • Disodium 1-hydroxyethylidenediphosphonate
  • Disodium ethane-1-hydroxy-1,1-diphosphonic acid
  • Disodium ethane-1-hydroxy-1-diphosphonate
  • Disodium ethanol-1,1-diphosphonate
  • Disodium ethydronate
  • Disodium etidronate
  • Etidron
  • Etidronic acid disodium salt
  • Fostex NZ 2
  • Ostedron
  • Phosphonic acid, (1-hydroxyethylidene)bis-,
  • Phosphonic acid, (1-hydroxyethylidene)di-, disodium salt
  • Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:2)
  • Sequion 10Na2
  • Sodium ethane-1-hydroxy-1,1-diphosphonate
  • Sodium ethidronate
  • Sodium ethydronate
  • Sodium etidronate
  • Turpinal 2NZ
  • Disodium (1-hydroxyethylidene)diphosphonate
  • EINECS 231-025-7
  • Ethane-1-hydroxy-1,1-diphosphonate, disodium salt
  • Ethane-1-hydroxy-1,1-diphosphonic acid, disodium salt
  • (1-Hydroxyethane-1,1-diyl)diphosphonic acid disodium salt
  • Etidronsaeure dinatriumsalz
  • UNII-M16PXG993G
  • (1-hydroxyethylidene)diphosphonic acid, disodium salt
  • 1-hydroxyethylidene-1,1-diphosphonic acid disodium salt
  • disodium (1-hydroxyethylidene)diphosphonate
  • disodium 1-hydroxyethylidene phosphonate
  • disodium dihydrogen (1-hydroxyethylidene)diphosphonate
  • disodium ethydronate
  • 187285-10-5

Applications:

Separation of Etidronate disodium on Newcrom R1 HPLC column

February 16, 2018
Separation of Etidronate disodium on Newcrom C18 HPLC column

Etidronate disodium can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Etidronate disodium
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.