Chlorpromazine hydrochloride

Chlorpromazine hydrochloride structural formula

CAS Number69-09-0
Molecular FormulaC17H20Cl2N2S
Molecular Weight355.321
InChI KeyFBSMERQALIEGJT-UHFFFAOYSA-N
LogP5.04
Synonyms
  • Chlorpromazine hydrochloride
  • 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine--hydrogen chloride (1/1)
  • 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, hydrochloride (1:1)
  • 69-09-0
  • 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, monohydrochloride
  • 10-(3-Dimethylaminopropyl)-2-chlorophenothiazine monohydrochloride
  • 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, hydrochloride (1:1)
  • 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine monohydrochloride
  • 2-Chloro-N,N-dimethyl-10H-phenothiazin-10-propanamine hydrochloride
  • Aminazin hydrochloride
  • Aminazin monohydrochloride
  • Ampliactil monohydrochloride
  • Chloractil
  • Chlorazin
  • Chloropromazine hydrochloride
  • Chloropromazine monohydrochloride
  • Chlorpromazine monohydrochloride
  • Chlorpromazine, chlorhydrate
  • Chlorpromazinhydrochlorid
  • Chlorpromazinium chloride
  • clorpromazinio, clorhidrato
  • Hebanil
  • Hibanil
  • Hibernal
  • Klorproman
  • Klorpromex
  • Largactil monohydrochloride
  • Largaktyl
  • Marazine
  • Megatil
  • Neurazine
  • Norcozine
  • Phenothiazine, 2-chloro-10-[3-(dimethylamino)propyl]-, monohydrochloride
  • Plegomazin
  • Promacid
  • Promapar
  • Propaphen
  • Propaphenin hydrochloride
  • Sonazine
  • Taroctyl
  • Thorazine hydrochloride
  • Torazina
  • Tranzene
  • Aminazinum
  • 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine monohydrochloride
  • Contomin hydrochloride
  • CPZ (VAN)
  • EINECS 200-701-3
  • Fenactil monohydrochloride
  • Hybernal
  • Lomazine
  • Megaphen hydrochloride
  • NCI-C05210
  • NSC 17479
  • Promachel
  • Promexin
  • Tranzine
  • Unitensen
  • Chlorpromazine hydrochloride intensol
  • Chlorpromazine HCl
  • UNII-9WP59609J6
  • 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine monohydrochloride
  • Chlorpromazine hydrochloride

Applications:

Separation of Chlorpromazine hydrochloride on Newcrom R1 HPLC column

February 19, 2018
Separation of Chlorpromazine hydrochloride on Newcrom C18 HPLC column

Chlorpromazine hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Chlorpromazine hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.